Paper published in Brain research
Computational modelling paper (looking at stimulus-specific adaptation) written by SCANDLE researcher Robert Mill and colleagues from Plymouth, published in Brain Research
Robert Mill, post-doctoral researcher on the SCANDLE project, has published, along with his fellow colleagues from Plymouth University (Martin Coath, Thomas Wennekers & Sue Denham), a paper in the journal Brain Research.
Entitled 'Characterising stimulus-specific adaptation using a multi-layer field model' the article analyses a neural field model of stimulus-specific adaptation (SSA). SSA is a process whereby neurons adapt to common stimuli but otherwise remain sensitive to other, rare stimuli, and has been proposed as a low-level substrate for abstract pattern processing. SSA is generally investigated using ‘oddball sequences’ of tones, in which one frequency is common, the other rare.
The model consists of an input and output layer which are connected via depressing synapses and SSA is generated by synapses associated with localised inputs undergoing depression due to repeated presentations of a stimulus. A network of integrate-and-fire neurons would require numerical integration over long periods of time to generate results. Field models offer an advantage in that they can provide immediate and analytical solution for given input sequences. The paper discusses two possible solutions: a convolution of two closed-form expressions and Gaussian curve approximations, and comments on the output of the model with relation to published physiological data.